Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17377389 | 0.88 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2884396 | 0.83 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8029752 | 0.83 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29509911 | 0.83 | CA12 (0.56) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31240957 | 0.83 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL667942 | 0.83 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9838572 | 0.81 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18855065 | 0.81 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8722412 | 0.78 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1038081 | 0.78 | CYP1A2 (0.42) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235764-B1 | CATALYSIS USING PHOSPHINE OXIDE COMPOUNDS | DU PONT (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-1294657-B1 | CATALYSIS USING PHOSPHINE OXIDE AND SULFOXIDE COMPOUNDS | DU PONT (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6762330-B2 | MAKING BIARYLS BY REACTING A GRIGNARD REAGENT AND AN ARYL HALIDE IN THE PRESENCE OF A TRANSITION METAL COMPLEX WITH A PHOSPHINE OXIDE OR PHOSPHINE SULFOXIDE (HP(=S) TYPE) AS CATALYST | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-07-13 | — | — | US | disclosed |
| US-6716984-B2 | CONTACTING PHOSPHINE COMPOUND OFTHE FORMULA XPR1R2, WHEREIN X IS A HALOGEN, WITH THE SOLID SUPPORT, RESULTING IN THE P IN THE PHOSPHINE ATTACHED INDIRECTLY OR DIRECTLY TO SOLID SUPPORT VIA A COVALENT BONDS, AND REPLACING R1 OR R2 GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-06 | — | — | US | disclosed |
| EP-1294657-A2 | CATALYSIS USING PHOSPHINE OXIDE AND SULFOXIDE COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2003-03-26 | — | — | EP | disclosed |
| EP-1274744-A2 | POLYMER-SUPPORTED SYNTHESIS OF HETEROATOM BIDENTATE LIGANDS FOR CATALYSIS | E.I. DUPONT DE NEMOURS AND COMPANY, Legal Patent Records Center (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020137974-A1 | Catalysis using phosphine oxide and sulfoxide compounds | DUPONT POLYMERS, INC. | 2002-09-26 | — | — | US | disclosed |
| EP-1235764-A1 | CATALYSIS USING PHOSPHINE OXIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-04 | — | — | EP | disclosed |
| US-20020077479-A1 | Polymer-supported synthesis of heteroatom bidentate ligands for catalysis | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-06-20 | — | — | US | disclosed |
| WO-2002000574-A2 | CATALYSIS USING PHOSPHINE OXIDE AND SULFOXIDE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2001079213-A2 | POLYMER-SUPPORTED SYNTHESIS OF HETEROATOM BIDENTATE LIGANDS FOR CATALYSIS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-10-25 | — | — | WO | disclosed |
| US-6291722-B1 | CONTACTING GRIGNARD REAGENT OF FORMULA R.SUP.7--MGX WITH AN ARYL COMPOUND OF THE FORMULA R.SUP.1--X IN THE PRESENCE OF A CATALYTIC AMOUNT OF COORDINATION COMPRISING TRASITION METAL COMPLEXED TO PHOSPHINE OXIDE TO PREPARE BISARYL COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY | 2001-09-18 | — | — | US | disclosed |
| WO-2001040147-A1 | CATALYSIS USING PHOSPHINE OXIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-06-07 | — | — | WO | disclosed |
| US-6124462-A | PREPARING ARYLAMINE AND BIARYLS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137974-A1 | Catalysis using phosphine oxide and sulfoxide compounds | TST, GSS, ARSA | CA12 3635/4885CA1 3990/4885CA2 4079/4885 |
| US-20020077479-A1 | Polymer-supported synthesis of heteroatom bidentate ligands for catalysis | PARG, PCNA, PARN | CA12 1077/4885CA1 1663/4885CA2 2502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.