Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.47 |
| ▸ | ACP1 | P24666 | 4/20 | 0.46 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679085 | 0.99 | TOP2A (0.46) | TOP2AHRH3ACP1SMARCA2TSHR | |
| SCHEMBL6679149 | 0.88 | TSHR (0.55) | TOP2AACP1SMARCA2TSHRACHE | |
| SCHEMBL6677139 | 0.84 | ACHE (0.48) | TOP2AACP1SMARCA2ACHE | |
| SCHEMBL6675351 | 0.83 | HRH3 (0.44) | HRH3ACHE | |
| SCHEMBL6678907 | 0.83 | ACHE (0.47) | TOP2AACP1SMARCA2TSHRACHE | |
| SCHEMBL6674578 | 0.83 | SRC (0.43) | TOP2AHRH3ACP1SMARCA2ACHE | |
| SCHEMBL6676209 | 0.82 | KMT5A (0.44) | ACP1 | |
| SCHEMBL2246009 | 0.81 | ACP1 (0.36) | TOP2AHRH3ACP1SMARCA2ACHE | |
| SCHEMBL2246141 | 0.81 | ACP1 (0.36) | TOP2AHRH3ACP1SMARCA2ACHE | |
| SCHEMBL6676198 | 0.80 | ACHE (0.38) | TOP2AHRH3ACP1SMARCA2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |