Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674245 | 1.00 | CHRM1 (0.55) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL6674242 | 1.00 | CHRM1 (0.55) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL13698916 | 0.91 | CHRM1 (0.51) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL21159381 | 0.83 | NR1H2 (0.47) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL21138276 | 0.83 | NR1H2 (0.47) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL1692091 | 0.81 | CHRM1 (0.44) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL31644355 | 0.80 | HSD11B1 (0.42) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| Water SCHEMBL27612759 | 0.79 | HSD11B1 (0.43) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL1692101 | 0.79 | CHRM1 (0.42) | CHRM1ALDH1A1L3MBTL1THRBATM | |
| SCHEMBL20521167 | 0.78 | HSD11B1 (0.41) | CHRM1ALDH1A1L3MBTL1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0899259-B1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-5932744-A | Process for the preparation of cis-hexahydroisoindoline derivatives | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0899259-A1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |