Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486150 | 0.84 | FOLH1 (0.50) | ALDH1A1HPGDFOLH1ALOX15TSHR | |
| SCHEMBL28088092 | 0.83 | FOLH1 (0.54) | ALDH1A1TRPA1MIFFOLH1ALOX15 | |
| SCHEMBL10425173 | 0.81 | FOLH1 (0.59) | ALDH1A1HPGDFOLH1ALOX15TSHR | |
| SCHEMBL11669456 | 0.77 | FOLH1 (0.55) | ALDH1A1HPGDFOLH1ALOX15TSHR | |
| SCHEMBL13525501 | 0.73 | MIF (0.52) | ALDH1A1TRPA1HPGDMIFCYP3A4 | |
| SCHEMBL41908 | 0.73 | MIF (0.52) | ALDH1A1TRPA1HPGDMIFCYP3A4 | |
| SCHEMBL4889213 | 0.73 | FOLH1 (0.50) | ALDH1A1HPGDFOLH1ALOX15TSHR | |
| SCHEMBL8763355 | 0.72 | MIF (0.56) | ALDH1A1TRPA1HPGDMIFCYP3A4 | |
| SCHEMBL968436 | 0.72 | FOLH1 (0.59) | ALDH1A1HPGDFOLH1ALOX15TSHR | |
| SCHEMBL70392 | 0.72 | FOLH1 (0.76) | ALDH1A1HPGDFOLH1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003060078-A9 | HETEROCYCLIC MODULATORS OF NUCLEAR RECEPTORS | X CEPTOR THERAPEUTICS INC (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2002020544-A1 | PROCESS FOR PREPARING PEPTIDE DERIVATIZED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2002-03-14 | — | — | WO | disclosed |