Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425173 | 0.82 | FOLH1 (0.59) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL31486150 | 0.74 | FOLH1 (0.50) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL30365583 | 0.73 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL69352 | 0.73 | TSHR (0.68) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL70392 | 0.73 | FOLH1 (0.76) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL14699641 | 0.73 | FOLH1 (0.49) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL6680027 | 0.73 | ALDH1A1 (0.50) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL30879601 | 0.72 | HIF1A (0.57) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL374696 | 0.71 | FOLH1 (0.61) | FOLH1ALDH1A1ALOX15TSHRKDM4E | |
| SCHEMBL28115 | 0.71 | FOLH1 (0.61) | FOLH1ALDH1A1ALOX15TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | BAYER CROPSCIENCE AG (DE) | 2008-10-30 | — | — | US | disclosed |
| CN-100344612-C | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER CROPSCIENCE GMBH (DE) | 2007-10-24 | — | — | CN | disclosed |
| US-7189848-B2 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER CROPSCIENCE GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| CN-1680310-A | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER CROPSCIENCE GMBH (DE) | 2005-10-12 | — | — | CN | disclosed |
| US-6884903-B2 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | AVENTIS CROPSCIENCE GMBH (DE) | 2005-04-26 | — | — | US | disclosed |
| US-20030208087-A1 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| US-6538150-B2 | Suitable for the preparation of herbicidal active substances such as sulfonylureas. | AVENTIS CROPSCIENCE GMBH (DE) | 2003-03-25 | — | — | US | disclosed |
| US-20020062029-A1 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269052-A1 | USE of PYRIDINE-2-OXY-3-CARBOXAMIDES AS SAFENERS | CBR3, CBR1, CYP4Z1 | FOLH1 3041/4885ALDH1A1 279/4885ALOX15 985/4885 |
| US-20030208087-A1 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | SLC5A1, DDT, ABCC1 | FOLH1 1385/4885ALDH1A1 15/4885ALOX15 2137/4885 |
| US-20020062029-A1 | Substituted sulfonylaminomethylbenzoic acid (derivatives) and their preparation | SLC5A1, DDT, ABCC1 | FOLH1 1385/4885ALDH1A1 15/4885ALOX15 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.