Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160023 | 0.87 | HRH3 (0.40) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL24688643 | 0.87 | HRH3 (0.40) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL22446838 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL21210881 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL18430268 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL23032896 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL22877461 | 0.85 | HRH3 (0.42) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL22363315 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL22990875 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 | |
| SCHEMBL18387974 | 0.85 | HRH3 (0.39) | ALDH1A1MAPTHRH3L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097924-B1 | 4-hydroxy-4-phenylpiperidine derivatives having opioid agonist activity and pharmaceuticals containing the same | SSP CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6362203-B1 | ANALGESICS | SSP CO., LTD (JP) | 2002-03-26 | — | — | US | disclosed |
| EP-1097924-A1 | 4-hydroxy-4-phenylpiperidine derivatives having -opioid agonist activity and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 2001-05-09 | — | — | EP | disclosed |