Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680123 | 1.00 | CYP2C9 (0.85) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6680121 | 1.00 | CYP2C9 (0.85) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6738653 | 0.92 | CYP2C9 (1.00) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6231450 | 0.92 | CYP2C9 (1.00) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6689164 | 0.90 | CYP2C9 (0.83) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6688517 | 0.88 | CYP2C9 (0.88) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6688520 | 0.88 | CYP2C9 (0.88) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6236224 | 0.88 | CYP2C9 (0.80) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6686493 | 0.88 | CYP2C9 (0.85) | CYP2C9NR1I2MAPK1HSD17B10PLK1 | |
| SCHEMBL6686492 | 0.88 | CYP2C9 (0.85) | CYP2C9NR1I2MAPK1HSD17B10PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | disclosed |