SCHEMBL6680170

SCHEMBL6680170

NC(=O)CCC(C(=O)O)C(O)(Cc1ccc2ccccc2c1)[PH2]=O.NC(=O)CCC(C(=O)O)C(O)(Cc1ccccc1-c1ccccc1)[PH2]=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
PPARG P37231 1/20 0.34
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
MC4R P32245 2/20 0.33
MC1R Q01726 2/20 0.33
MC5R P33032 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
SOX18 P35713 1/20 0.33
FFAR1 O14842 2/20 0.33
FFAR4 Q5NUL3 2/20 0.33
CYP1A2 P05177 1/20 0.33
MME P08473 1/20 0.32
ACE P12821 1/20 0.32
CPA1 P15085 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
CASR P41180 2/20 0.32
ICMT O60725 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4871616 0.90 SLC1A3 (0.39) PPARGPPARDPPARAMC4RMC1R
SCHEMBL4868966 0.89 KMT2A (0.43) KMT2AFFAR1FFAR4MMEACE
SCHEMBL6682067 0.80 GGPS1 (0.45) KMT2AFFAR1FFAR4TPH1
SCHEMBL4871624 0.73 SLC1A3 (0.39) PPARGPPARDPPARAMC4RMC1R
SCHEMBL4868661 0.73 KIF11 (0.35) KMT2AFFAR1CPA1
SCHEMBL4868970 0.72 KMT2A (0.43) KMT2AFFAR1FFAR4MMEACE
SCHEMBL4873572 0.71 FFAR1 (0.36) PPARGPPARASLC1A3SLC1A2SLC1A1
SCHEMBL4874210 0.69 CYP26B1 (0.43) PPARG
SCHEMBL4874704 0.69 CYP26B1 (0.36) PPARG
SCHEMBL4874787 0.67 GRIK1 (0.39) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048394-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2004-06-10 WO disclosed