SCHEMBL6680358

SCHEMBL6680358

CCC1(CC)c2ccccc2-c2ccc(-c3c4ccccc4c(-c4ccccc4)c4ccccc34)cc21

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 15/20 0.39
APEX1 P27695 1/20 0.34
ACHE P22303 1/20 0.33
PGR P06401 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6683913 0.95 PDK2 (0.38) PDK2APEX1PGR
SCHEMBL6684790 0.88 PDK2 (0.37) PDK2
SCHEMBL10153158 0.88 PDK2 (0.47) PDK2ACHE
SCHEMBL10153926 0.88 PDK2 (0.47) PDK2ACHE
SCHEMBL4370411 0.87 ALOX5 (0.43) PDK2PGR
SCHEMBL10153552 0.87 PDK2 (0.46) PDK2ACHE
SCHEMBL14600454 0.87 PDK2 (0.46) PDK2ACHE
SCHEMBL10153373 0.87 PDK2 (0.44) PDK2
SCHEMBL10153949 0.87 PDK2 (0.44) PDK2
SCHEMBL3886407 0.86 PDK2 (0.39) PDK2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004053018-A1 ELECTROLUMINESCENT DEVICES XIE SHUANG (CA) 2004-06-24 WO disclosed
US-20030215667-A1 Electroluminescent devices ELIGHT CORPORATION (VG) 2003-11-20 US disclosed