Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474396 | 1.00 | LMNA (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL6680394 | 1.00 | LMNA (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL9474399 | 1.00 | LMNA (0.53) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL28444370 | 0.96 | CYP3A4 (0.55) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL9245210 | 0.93 | CYP3A4 (0.55) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL9245202 | 0.93 | CYP3A4 (0.55) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL19996603 | 0.93 | LMNA (0.60) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL18405976 | 0.93 | LMNA (0.60) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL31542561 | 0.93 | LMNA (0.60) | LMNAMEN1USP2ALDH1A1CYP3A4 | |
| SCHEMBL5188564 | 0.93 | LMNA (0.60) | LMNAMEN1USP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048499-A2 | COMBINED ROD-DISC CRYSTALLINE SYSTEMS WITH NEMATIC PROPERTIES | THE UNIVERSITY OF HULL (GB) | 2004-06-10 | — | — | WO | disclosed |