Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30900827 | 1.00 | HSD11B1 (0.43) | HSD11B1DHFRATMMEN1KMT2A | |
| SCHEMBL13127431 | 0.88 | HSD11B1 (0.43) | HSD11B1DHFRATMMEN1KMT2A | |
| SCHEMBL23907118 | 0.83 | HSD11B1 (0.38) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL15100385 | 0.83 | PTPN1 (0.43) | HSD11B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15100426 | 0.83 | PTPN1 (0.43) | HSD11B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15100429 | 0.83 | PTPN1 (0.43) | HSD11B1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL15100422 | 0.82 | HSD11B1 (0.40) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL15102152 | 0.82 | HSD11B1 (0.43) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL7172082 | 0.82 | HSD11B1 (0.40) | HSD11B1DHFRMEN1KMT2ATNK2 | |
| SCHEMBL15100421 | 0.82 | HSD11B1 (0.40) | HSD11B1DHFRATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12234402-B2 | Mesogen compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2025-02-25 | — | — | US | disclosed |
| CN-113122269-B | Ultraviolet light absorber | 光学转变公司 | 2024-05-28 | — | — | CN | disclosed |
| US-20230383187-A1 | Mesogen Compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-11-30 | — | — | US | disclosed |
| CN-113122269-A | Ultraviolet light absorber | 光学转变公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-107109227-B | Ultraviolet light absorber | 光学转变公司 | 2021-05-04 | — | — | CN | disclosed |
| US-10619098-B2 | Ultraviolet light absorbers | TRANSITIONS OPTICAL, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| EP-3201292-B1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL INC (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. | 2017-09-28 | — | — | US | disclosed |
| EP-3201292-A1 | ULTRAVIOLET LIGHT ABSORBERS | Transitions Optical, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2016053662-A1 | ULTRAVIOLET LIGHT ABSORBERS | TRANSITIONS OPTICAL, INC. (US) | 2016-04-07 | — | — | WO | disclosed |
| WO-2004044631-A1 | CHOLESTERIC COLOR FILTER AND METHOD OF MANUFACTURING SUCH | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2004-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10619098-B2 | Ultraviolet light absorbers | ERCC1, MCM4, ERCC4 | HSD11B1 1807/4885DHFR 821/4885ATM 1701/4885 |
| US-20170275534-A1 | ULTRAVIOLET LIGHT ABSORBERS | MCM4, ERCC1, ERCC4 | HSD11B1 2076/4885DHFR 882/4885ATM 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.