SCHEMBL6680593

SCHEMBL6680593

CCCC(Cl)Cc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.46
TAAR1 Q96RJ0 4/20 0.45
SLC6A2 P23975 2/20 0.45
MAOA P21397 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45
CYP2A6 P11509 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
EPHX1 P07099 1/20 0.43
TRPA1 O75762 1/20 0.42
TP53 P04637 1/20 0.42
CSNK1E P49674 1/20 0.42
SLC18A2 Q05940 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL6659821 0.98 SIGMAR1 (0.44) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL11874051 0.88 CSNK1E (0.47) SIGMAR1TAAR1SLC6A2MAOASLC6A4
SCHEMBL11865658 0.84 CSNK1E (0.57) TP53CSNK1E
SCHEMBL11871999 0.84 CSNK1E (0.57) TP53CSNK1E
SCHEMBL6559365 0.84 CSNK1E (0.57) TP53CSNK1E
SCHEMBL11861606 0.84 CSNK1E (0.57) TP53CSNK1E
SCHEMBL11874146 0.84 CSNK1E (0.57) TP53CSNK1E
Ammonia Solution, Strong SCHEMBL28800228 0.83 CSNK1E (0.55) TP53CSNK1E
Ammonia Solution, Strong SCHEMBL10939844 0.83 CSNK1E (0.55) TP53CSNK1E
SCHEMBL11453966 0.82 SIGMAR1 (0.40) SIGMAR1TAAR1SLC6A2MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114292247-A Disulfide compound and method for catalyzing benzyl oxidation of alkyl aromatic compound by using disulfide compound 大连理工大学 2022-04-08 CN disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed