Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HAT1 | O14929 | 3/20 | 0.32 |
| ▸ | EP300 | Q09472 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677114 | 0.93 | CA2 (0.33) | PTGER4ADRB3ADRB1CA2CHRM2 | |
| SCHEMBL6681055 | 0.91 | PTGER4 (0.35) | PTGER4ADRB3ADRB1CA2 | |
| SCHEMBL6679724 | 0.86 | PTGER4 (0.32) | PTGER4ADRB3ADRB1CA2CA12 | |
| SCHEMBL6681183 | 0.86 | PTGER4 (0.32) | PTGER4ADRB3ADRB1CA2 | |
| SCHEMBL6677604 | 0.86 | PTGER4 (0.32) | PTGER4ADRB3ADRB1CA2CA12 | |
| SCHEMBL6676709 | 0.85 | MEN1 (0.32) | PTGER4ADRB3CA2 | |
| SCHEMBL6679366 | 0.83 | ADRB3 (0.39) | ADRB3ADRB1CA2HAT1EP300 | |
| SCHEMBL6804698 | 0.82 | PTGER4 (0.37) | PTGER4ADRB3ADRB1CA2CHRM2 | |
| SCHEMBL6680691 | 0.82 | PTGER4 (0.37) | PTGER4ADRB3ADRB1CA2CHRM2 | |
| SCHEMBL6680679 | 0.76 | ADRB3 (0.36) | ADRB3ADRB1CA2HAT1EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |