Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 4/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL6 | P05231 | 1/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 1/20 | 0.59 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13692216 | 0.91 | HIF1A (0.70) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13694230 | 0.90 | HIF1A (0.66) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655931 | 0.89 | HIF1A (0.66) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655987 | 0.89 | HIF1A (0.68) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655947 | 0.89 | HIF1A (0.70) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655943 | 0.87 | HIF1A (0.78) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655939 | 0.85 | HIF1A (0.79) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL15662128 | 0.84 | PGR (0.78) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13655915 | 0.84 | HIF1A (0.67) | HIF1ALMNAPGRNR3C1HSD17B10 | |
| SCHEMBL13692238 | 0.84 | HIF1A (0.70) | HIF1ALMNAPGRNR3C1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470150-A2 | CORTICOSTEROIDS NITRATE DERIVATIVES | Nicox S.A. (FR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064443-A2 | NEW CORTICOSTEROIDS | NICOX S.A. (FR) | 2003-08-07 | — | — | WO | disclosed |