SCHEMBL668138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL668686	0.87	ALDH1A1 (0.49)	HTTHIF1ATSHRALDH1A1KDM4E
	SCHEMBL291506	0.79	TP53 (0.47)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL23453516	0.79	TP53 (0.59)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL22799778	0.78	CYP3A4 (0.50)	HTTTP53FOLH1MRGPRX4TSHR
	SCHEMBL28857874	0.76	HTT (0.50)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL12164265	0.76	KDM4E (0.55)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL534811	0.76	HTT (0.56)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL31617745	0.76	HTT (0.56)	HTTTP53CYP2C9HIF1AFOLH1
	SCHEMBL6043415	0.73	TP53 (0.50)	HTTTP53CYP2C9HIF1AFOLH1
	Phthalic Acid SCHEMBL31538471	0.73	ALDH1A1 (0.64)	HTTTP53TSHRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.