Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.51 |
| ▸ | REN | P00797 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PEPD | P12955 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30899064 | 1.00 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL6681470 | 1.00 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL29380436 | 0.94 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL29405754 | 0.94 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL29615543 | 0.89 | ACE (0.51) | ACERENKDM4EF2LMNA | |
| SCHEMBL14895624 | 0.88 | CAPN1 (0.41) | ACEREN | |
| SCHEMBL30248996 | 0.87 | ACE (0.61) | ACERENKDM4EF2LMNA | |
| SCHEMBL30069048 | 0.86 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL13246639 | 0.85 | ACE (0.64) | ACERENKDM4EF2LMNA | |
| SCHEMBL6679097 | 0.85 | DPP4 (0.58) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118421681-A | OsSERK4 protein and application of coding gene thereof in regulation and control of plant resistance to rice grass dwarf virus | 福建农林大学 | 2024-08-02 | — | — | CN | disclosed |
| EP-1476746-A2 | METHOD FOR DISCOVERING PHARMACOLOGICALLY ACTIVE SUBSTANCES | Paion GmbH (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003071268-A2 | METHOD FOR DISCOVERING PHARMACOLOGICALLY ACTIVE SUBSTANCES | PAION GMBH (DE) | 2003-08-28 | — | — | WO | disclosed |
| US-4719200-A | Amino acid derivatives and antihypertensive drugs containing the same | AJINOMOTO CO., INC. (JP) | 1988-01-12 | — | — | US | disclosed |