Sugi Predict

Sugi Predict / Compounds / SCHEMBL29615543

SCHEMBL29615543

SCHEMBL29615543

N[C@@H](CO)C(=O)N1CCCC[C@H]1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 6/20 0.51
▸ REN P00797 4/20 0.51
▸ LTA4H P09960 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ F2 P00734 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ PEPD P12955 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ PTGS1 P23219 1/20 0.51
▸ HTR2A P28223 1/20 0.51
▸ PTGS2 P35354 1/20 0.51
▸ HRH1 P35367 1/20 0.51
▸ THPO P40225 1/20 0.51
▸ PMP22 Q01453 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ ACE2 Q9BYF1 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29380436 0.95 ACE (0.56) ACERENLTA4HKDM4EF2
SCHEMBL29405754 0.95 ACE (0.56) ACERENLTA4HKDM4EF2
SCHEMBL6681470 0.89 ACE (0.51) ACERENLTA4HKDM4EF2
SCHEMBL6681472 0.89 ACE (0.51) ACERENLTA4HKDM4EF2
SCHEMBL30899064 0.89 ACE (0.51) ACERENLTA4HKDM4EF2
SCHEMBL29663652 0.87 ACE (0.51) ACERENLTA4HKDM4EF2
SCHEMBL30452048 0.82 CAPN1 (0.48) ACERENLTA4HKDM4EF2
SCHEMBL2739551 0.82 ACE (0.56) ACERENLTA4HKDM4EF2
SCHEMBL30203686 0.82 DPP4 (0.44) ACERENLTA4HKDM4EF2
SCHEMBL29615512 0.82 ACE (0.52) ACERENLTA4HKDM4EF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-28 — — US disclosed
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 — — US disclosed
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-03-12 — — US disclosed
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-08 — — US disclosed
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS OHIO STATE INNOVATION FOUNDATION (US) 2026-01-01 — — US disclosed
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2025-10-28 — — US disclosed
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. 2025-07-31 — — US disclosed
US-20240360174-A1 CELL-PENETRATING PEPTIDE SEQUENCES OHIO STATE INNOVATION FOUNDATION 2024-10-31 — — US disclosed
US-20240245790-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. 2024-07-25 — — US disclosed
US-11987647-B2 Cyclic cell-penetrating peptides with one or more hydrophobic residues OHIO STATE INNOVATION FOUNDATION (US) 2024-05-21 — — US disclosed
US-20240158445-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH THREE OR MORE HYDROPHOBIC RESIDUES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-05-16 — — US disclosed
US-11878046-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2024-01-23 — — US disclosed
US-20220306693-A1 CYCLIC CELL PENETRATING PEPTIDES COMPRISING BETA-HAIRPIN MOTIFS AND METHODS OF MAKING AND USING THEREOF OHIO STATE INNOVATION FOUNDATION 2022-09-29 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof OHIO STATE INNOVATION FOUNDATION (US) 2022-06-07 — — US disclosed
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-05-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (20 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352394-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof VIP, LNPEP, IAPP ACE 3502/4885REN 3039/4885LTA4H 3341/4885
US-20260008816-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF SLC3A2, SPPL2B, SLC7A1 ACE 3419/4885REN 3017/4885LTA4H 4750/4885
US-11878046-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof IKBKE, IKBKB, SHARPIN ACE 4573/4885REN 4648/4885LTA4H 1892/4885
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES SLC47A1, SLC47A2, VIP ACE 4080/4885REN 3750/4885LTA4H 4143/4885
US-20240245790-A1 CYCLIC CELL PENETRATING PEPTIDES SLC47A1, SLC47A2, VIP ACE 4080/4885REN 3750/4885LTA4H 4143/4885
US-20260008812-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC38A7, SLC7A1, SLC6A7 ACE 1939/4885REN 1257/4885LTA4H 3540/4885
US-20260146063-A1 CYCLIC CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, SLC7A1, SLC6A15 ACE 1946/4885REN 1662/4885LTA4H 3911/4885
US-20220306693-A1 CYCLIC CELL PENETRATING PEPTIDES COMPRISING BETA-HAIRPIN MOTIFS AND METHODS OF MAKING AND USING THEREOF CHN2, TAP2, VIP ACE 3325/4885REN 2618/4885LTA4H 3866/4885
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF SLC7A1, TAP1, SLC7A5 ACE 3598/4885REN 4125/4885LTA4H 3968/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 ACE 3899/4885REN 3405/4885LTA4H 3322/4885
US-20260070947-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 ACE 2843/4885REN 2030/4885LTA4H 4237/4885
US-20220160819-A1 DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF IKBKE, IKBKB, SHARPIN ACE 4573/4885REN 4648/4885LTA4H 1892/4885
US-20260070948-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH CARGO SLC7A1, SLC38A7, SLC6A19 ACE 2988/4885REN 2481/4885LTA4H 3988/4885
US-11351222-B2 Di-sulfide containing cell penetrating peptides and methods of making and using thereof IKBKE, IKBKB, SHARPIN ACE 4573/4885REN 4648/4885LTA4H 1892/4885
US-20260001916-A1 CYCLIC CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 ACE 2236/4885REN 2364/4885LTA4H 3206/4885
US-12454552-B2 Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof CHN2, TAP2, VIP ACE 3325/4885REN 2618/4885LTA4H 3866/4885
US-20260008813-A1 CELL-PENETRATING PEPTIDE COMPOUNDS SLC7A1, SLC38A7, SLC6A19 ACE 2506/4885REN 1284/4885LTA4H 3896/4885
US-20240158445-A1 CYCLIC CELL-PENETRATING PEPTIDES WITH THREE OR MORE HYDROPHOBIC RESIDUES SLC3A2, SLC7A1, ARGLU1 ACE 4661/4885REN 4059/4885LTA4H 4191/4885
US-20240360174-A1 CELL-PENETRATING PEPTIDE SEQUENCES VIP, LNPEP, NGLY1 ACE 3539/4885REN 3492/4885LTA4H 3236/4885
US-11987647-B2 Cyclic cell-penetrating peptides with one or more hydrophobic residues VIP, LNPEP, TAP1 ACE 4059/4885REN 4229/4885LTA4H 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.