Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 17/20 | 0.78 |
| ▸ | FABP3 | P05413 | 3/20 | 0.78 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6691438 | 0.88 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6687926 | 0.86 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6687638 | 0.85 | FABP4 (0.70) | FABP4FABP3 | |
| SCHEMBL6686602 | 0.85 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6686562 | 0.85 | FABP4 (0.76) | FABP4FABP3 | |
| SCHEMBL6685978 | 0.84 | FABP4 (0.77) | FABP4FABP3 | |
| SCHEMBL6690128 | 0.83 | FABP4 (0.86) | FABP4FABP3 | |
| SCHEMBL6691701 | 0.81 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6695776 | 0.81 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6688429 | 0.81 | FABP4 (0.80) | FABP4FABP3HDAC1HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| US-20140363522-A1 | Compositions and Methods for Treating and/or Preventing Cancer by Inhibiting Fatty Acid Binding Proteins | NIH - DEITR | 2014-12-11 | — | — | US | disclosed |
| US-8748470-B2 | Methods for treating ovarian cancer by inhibiting fatty acid binding proteins | THE UNIVERSITY OF CHICAGO (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120289570-A1 | COMPOSITIONS AND METHODS FOR TREATING AND/OR PREVENTING CANCER BY INHIBITING FATTY ACID BINDING PROTEINS | NIH | 2012-11-15 | — | — | US | disclosed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |