Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676121 | 0.88 | CA1 (0.46) | KMT2ACA2CA1NAMPTNQO2 | |
| SCHEMBL6680713 | 0.86 | KMT2A (0.44) | KMT2AMEN1CA2CA1NAMPT | |
| SCHEMBL6675049 | 0.85 | KMT2A (0.55) | KMT2AMEN1ATMCA2CA1 | |
| SCHEMBL27478756 | 0.84 | MEN1 (0.50) | KMT2AMEN1ATMCA2CA1 | |
| SCHEMBL27564399 | 0.81 | MEN1 (0.43) | KMT2AMEN1ATMCA2CA1 | |
| SCHEMBL2876045 | 0.81 | NAMPT (0.60) | CA2CA1NAMPTMAPTSMN1; SMN2 | |
| SCHEMBL6680633 | 0.81 | CA2 (0.49) | CA2CA1NAMPTNQO2MAPT | |
| SCHEMBL7248116 | 0.80 | CA1 (0.43) | KMT2AMEN1ATMCA2CA1 | |
| SCHEMBL17740765 | 0.79 | CA1 (0.47) | CA2CA1NAMPTNQO2MAPT | |
| SCHEMBL6675643 | 0.79 | CYP3A4 (0.49) | KMT2AMEN1CA2CA1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |