Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | HAT1 | O14929 | 4/20 | 0.39 |
| ▸ | EP300 | Q09472 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679246 | 0.88 | ADORA1 (0.40) | HAT1EP300KMT2ASLC2A1ADRB3 | |
| SCHEMBL6678770 | 0.87 | ADRB3 (0.43) | HAT1EP300ADRB3ADRB1 | |
| SCHEMBL6679483 | 0.85 | SLC2A1 (0.39) | HAT1EP300SLC2A1ADRB3ADRB1 | |
| SCHEMBL6679282 | 0.85 | SLC2A1 (0.39) | HAT1EP300SLC2A1ADRB3ADRB1 | |
| SCHEMBL6679530 | 0.84 | ADORA1 (0.38) | KMT2ASLC2A1ADRB3ADRB1ADRB2 | |
| SCHEMBL6269328 | 0.82 | KDM4E (0.41) | HAT1EP300MEN1KMT2AADRB3 | |
| SCHEMBL6272839 | 0.82 | KMT2A (0.42) | KMT2ASLC2A1ADRB3ADRB1 | |
| SCHEMBL6679815 | 0.81 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6679821 | 0.81 | ADRB3 (0.55) | ADRB3ADRB1 | |
| SCHEMBL6272444 | 0.81 | ADRB3 (0.43) | KMT2AADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |