Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HAT1 | O14929 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679530 | 0.95 | ADORA1 (0.38) | ADORA1KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6681939 | 0.90 | ADRB3 (0.38) | ADORA1KDM4EALDH1A1ALOX15HSD17B10 | |
| SCHEMBL6687818 | 0.89 | ADRB3 (0.39) | ADORA1ALDH1A1HAT1EP300ADRB1 | |
| SCHEMBL6681905 | 0.88 | TUBB (0.41) | HAT1EP300ADRB1ADRB3ADRB2 | |
| SCHEMBL6269328 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HAT1EP300HPGD | |
| SCHEMBL6678770 | 0.85 | ADRB3 (0.43) | HAT1EP300ADRB1ADRB3 | |
| SCHEMBL6677081 | 0.85 | CYP4F2 (0.42) | ALDH1A1ADRB1ADRB3ADRB2TP53 | |
| SCHEMBL6679483 | 0.83 | SLC2A1 (0.39) | HAT1EP300ADRB1ADRB3ADRB2 | |
| SCHEMBL6679282 | 0.83 | SLC2A1 (0.39) | HAT1EP300ADRB1ADRB3ADRB2 | |
| Hydrochloric Acid SCHEMBL6679004 | 0.82 | ADRB3 (0.53) | ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |