SCHEMBL668192

SCHEMBL668192

CCOC(=O)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
LMNA P02545 1/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAOA P21397 1/20 0.59
MAPT P10636 5/20 0.54
PDK1 Q15118 1/20 0.54
PDK2 Q15119 1/20 0.54
PDK3 Q15120 1/20 0.54
PDK4 Q16654 1/20 0.54
CES2 O00748 1/20 0.53
CES1 P23141 1/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294507 0.95 MAPT (0.57) CA12CA1CA2CA7CA9
SCHEMBL21656669 0.92 CA12 (0.53) CA12CA1CA2CA7CA9
Oxirane SCHEMBL958736 0.92 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL16664045 0.92 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL18821712 0.91 MAPT (0.64) CA12CA1CA2CA7CA9
SCHEMBL5442259 0.91 KDR (0.59) CA12CA1CA2CA7CA9
SCHEMBL1742368 0.87 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL5203063 0.87 MAPT (0.63) CA12CA1CA2CA7CA9
SCHEMBL5207670 0.87 PRF1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL23817292 0.86 MAPT (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN claimed
CN-120020114-A Preparation method of N-alkenyl amide compound 中国石油化工股份有限公司 2025-05-20 CN claimed
US-10224485-B2 Process for preparing a crystalline organic semiconductor material BASF SE (DE) 2019-03-05 US claimed
CN-107540583-A A kind of method for synthesizing the trifluoromethylbenzoic acid ethyl ester of 2 methyl mercapto 4 连云港世杰农化有限公司 2018-01-05 CN claimed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-4397763-A TITANIUM-BASED PHILLIPS PETROLEUM COMPANY (US) 1983-08-09 US claimed
US-4330648-A MIXTURE OF TITANIUM HALIDE, MAGNESIUM OR MANGANOUS CHLORIDE DIHYDROCARBYLALUMINUM HALIDE OR HYDRIDE AND AN ETHER-ALCOHOL PHILLIPS PETROLEUM COMPANY (US) 1982-05-18 US claimed
US-4312784-A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANOUS CHLORIDE, UNSATURATED HYDROCARBON AND TRIHYDROCARBYLALUMNIUM PHILLIPS PETROLEUM CO. (US) 1982-01-26 US claimed
US-4242480-A TWO OR THREE COMPONENT SYSTEM COMPRISING A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANESE CHLORIDE, UNSATURATED HYDROCARBON, ORGANOALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1980-12-30 US claimed
US-4234710-A TITANIUM HALIDE, MAGNESIUM OR MANGANESE HALIDE, ORGANOALUMINUM, LEWIS BASE, DIORGANOALUMINUM HALIDE PHILLIPS PETROLEUM COMPANY (US) 1980-11-18 US claimed
EP-0002522-A1 Process for polymerizing butene-1 PHILLIPS PETROLEUM COMPANY (US) 1979-06-27 EP claimed
EP-0002521-A1 Titanium-magnesium/manganese-aluminum catalyst and process for olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1979-06-27 EP claimed
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME CUREVERSE INCORPORATED (KR) 2025-06-19 US disclosed
CN-120020115-A Process for the preparation of N- (alkyl-2-hydroxy) alkylamides and N-alkenylamides 中国石油化工股份有限公司 2025-05-20 CN disclosed
CN-115710227-B Preparation method of indenoisoquinoline derivative 深圳万知达企业管理有限公司 2025-03-18 CN disclosed
US-4189554-A REACTING ORGANIC HALIDE AND MAGNESIUM METAL, CONTACTING WITH TITANIUM TETRAHALIDE; POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US disclosed
EP-0002522-A1 Process for polymerizing butene-1 PHILLIPS PETROLEUM COMPANY (US) 1979-06-27 EP disclosed
EP-0002521-A1 Titanium-magnesium/manganese-aluminum catalyst and process for olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1979-06-27 EP disclosed
US-4107412-A COORDINATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1978-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250197363-A1 THIADIAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, INCLUDING SAME PPARD, PPARG, PPARA CA12 4884/4885CA1 4883/4885CA2 4739/4885
US-10224485-B2 Process for preparing a crystalline organic semiconductor material STOM, SPOP, TTR CA12 299/4885CA1 140/4885CA2 458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.