Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.30 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217017 | 0.86 | CCR5 (0.37) | CCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6671389 | 0.80 | BACE1 (0.40) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5268319 | 0.69 | PDE4A (0.38) | STING1CCR5PDE4APDE4BPDE4C | |
| SCHEMBL18427309 | 0.68 | STING1 (0.46) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5267159 | 0.68 | STING1 (0.46) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18427349 | 0.68 | STING1 (0.46) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9778645 | 0.68 | PDE4A (0.44) | CCR5PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16016989 | 0.68 | PDE4A (0.42) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17358246 | 0.68 | STING1 (0.42) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17358236 | 0.68 | STING1 (0.42) | STING1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169304-B1 | 8-8, 6-6 AND 6-8 CATECHIN AND EPICATECHIN DIMERS AND METHODS FOR THEIR PREPARATION | MARS INC (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6156912-A | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation | MARS, INCORPORATED (US) | 2000-12-05 | — | — | US | disclosed |