Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 10/20 | 0.74 |
| ▸ | MMP2 | P08253 | 6/20 | 0.74 |
| ▸ | MMP9 | P14780 | 6/20 | 0.74 |
| ▸ | MMP3 | P08254 | 5/20 | 0.74 |
| ▸ | MMP1 | P03956 | 4/20 | 0.74 |
| ▸ | MMP7 | P09237 | 4/20 | 0.74 |
| ▸ | MMP8 | P22894 | 4/20 | 0.74 |
| ▸ | MMP13 | P45452 | 4/20 | 0.74 |
| ▸ | MMP14 | P50281 | 4/20 | 0.74 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.74 |
| ▸ | MMP15 | P51511 | 1/20 | 0.46 |
| ▸ | MMP16 | P51512 | 1/20 | 0.46 |
| ▸ | ADAM33 | Q9BZ11 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282217 | 0.85 | ADAM17 (1.00) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL4197995 | 0.84 | ADAM17 (0.88) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL6685079 | 0.84 | ADAM17 (0.79) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL6350418 | 0.84 | ADAM17 (1.00) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL6350415 | 0.84 | ADAM17 (1.00) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL1021287 | 0.84 | ADAM17 (1.00) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL4205891 | 0.83 | ADAM17 (1.00) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL6685255 | 0.82 | ADAM17 (0.84) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL6681788 | 0.82 | ADAM17 (0.84) | ADAM17MMP2MMP9MMP3MMP1 | |
| SCHEMBL4203684 | 0.81 | ADAM17 (0.69) | ADAM17MMP2MMP9MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060212-A1 | ANTI-INFLAMMATORY COATING FOR IMPLANTABLE MEDICAL DEVICES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-22 | — | — | WO | claimed |