Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AGXT | P21549 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492197 | 0.84 | TSHR (0.43) | IDO1AGXTMAOBCYP1A2 | |
| SCHEMBL6680175 | 0.82 | IDO1 (0.61) | IDO1AGXTMAOBABCB1HTR1A | |
| SCHEMBL13263642 | 0.75 | MAOB (0.79) | IDO1AGXTMAOBABCB1HTR1A | |
| SCHEMBL28460724 | 0.74 | ENPP2 (0.49) | MAOBENPP2 | |
| SCHEMBL26743095 | 0.74 | SMN1; SMN2 (0.44) | CYP1A2 | |
| SCHEMBL3389080 | 0.73 | IDO1 (0.67) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL1144902 | 0.73 | IDO1 (0.67) | IDO1AGXTMAOBSIGMAR1ABCB1 | |
| SCHEMBL20678539 | 0.73 | CA4 (0.39) | ENPP2 | |
| SCHEMBL22873 | 0.73 | MAOB (0.70) | IDO1AGXTMAOBABCB1HTR1A | |
| SCHEMBL9663664 | 0.73 | NPC1 (0.55) | IDO1AGXTMAOBMRGPRX4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137641-B1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6500951-B1 | RING CLOSING A CARBOXYLIC ACID DERIVATIVE IN PRESENCE OF A NITROGEN CONTAINING AROMATIC COMPOUND AND A BORON COMPOUND; HIGH YIELD AND PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-31 | — | — | US | disclosed |