SCHEMBL6682508

SCHEMBL6682508

CCCCCc1ccc(CCCC)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.70
ESR1 P03372 2/20 0.70
ADRA2A P08913 2/20 0.70
ADORA3 P0DMS8 2/20 0.70
TACR2 P21452 2/20 0.70
SLC6A2 P23975 2/20 0.70
SLC6A4 P31645 2/20 0.70
SLC6A3 Q01959 2/20 0.70
HSD17B10 Q99714 2/20 0.70
KDM4E B2RXH2 1/20 0.70
LMNA P02545 1/20 0.70
SHBG P04278 1/20 0.70
TP53 P04637 1/20 0.70
CYP3A4 P08684 1/20 0.70
HSPD1 P10809 1/20 0.70
ADRB3 P13945 1/20 0.70
HTR2C P28335 1/20 0.70
HSPE1 P61604 1/20 0.70
HIF1A Q16665 1/20 0.70
TST Q16762 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5426427 0.97 ESR1 (0.74) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL6684819 0.97 ESR1 (0.74) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL10863129 0.97 ESR1 (0.74) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL8508426 0.97 ESR1 (0.74) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL6682161 0.97 ESR1 (0.74) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL10568421 0.97 ALDH1A1 (0.65) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL181089 0.97 ESR1 (0.73) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL10568240 0.97 ESR1 (0.73) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL10567971 0.94 ALDH1A1 (0.70) ALDH1A1ESR1ADRA2AADORA3TACR2
SCHEMBL23849704 0.94 ESR1 (0.77) ALDH1A1ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011936-A1 FLUOROPOLYETHER-GROUP-CONTAINING POLYMER, SURFACE TREATMENT AGENT, AND ARTICLE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-15 EP disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
CN-1067992-C Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 2001-07-04 CN disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
CN-1184105-A Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 1998-06-10 CN disclosed
CN-1037842-C Substituted thiazolidine derivatives, pharmaceutical compositions and uses thereof OTSUKA PHARMA CO LTD (JP) 1998-03-25 CN disclosed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN disclosed