Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.50 |
| ▸ | MMP12 | P39900 | 12/20 | 0.50 |
| ▸ | MMP13 | P45452 | 10/20 | 0.50 |
| ▸ | MMP14 | P50281 | 10/20 | 0.50 |
| ▸ | MMP8 | P22894 | 8/20 | 0.50 |
| ▸ | MMP16 | P51512 | 8/20 | 0.50 |
| ▸ | MMP9 | P14780 | 11/20 | 0.47 |
| ▸ | MMP3 | P08254 | 8/20 | 0.47 |
| ▸ | MMP1 | P03956 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676499 | 0.81 | ESR1 (0.44) | MMP2MMP12MMP13MMP14MMP8 | |
| SCHEMBL29185447 | 0.77 | PARP10 (0.55) | MAPTTDP1L3MBTL1PARP10PKM | |
| SCHEMBL11775909 | 0.76 | PARP10 (0.61) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL12123501 | 0.76 | MAPT (0.72) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL9528723 | 0.73 | SMN1; SMN2 (0.61) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL26039005 | 0.72 | SMN1; SMN2 (0.59) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL9806485 | 0.71 | PARP10 (0.54) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL9806487 | 0.71 | ELANE (0.58) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL20546617 | 0.71 | MAPT (0.60) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 | |
| SCHEMBL27511781 | 0.71 | PLG (0.64) | MAPTTDP1L3MBTL1SMN1; SMN2PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |