Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682728 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL3260614 | 0.90 | MEN1 (0.41) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL3260618 | 0.90 | MEN1 (0.41) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL6541657 | 0.83 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL11366062 | 0.81 | NPC1 (0.52) | ALDH1A1TDP1CYP1A2HPGDKDM4E | |
| SCHEMBL17386515 | 0.81 | TLR8 (0.40) | ALDH1A1TDP1CYP1A2HPGDKCNA3 | |
| SCHEMBL11366065 | 0.81 | NPC1 (0.52) | ALDH1A1TDP1CYP1A2HPGDKDM4E | |
| SCHEMBL6540677 | 0.81 | MAPT (0.41) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL6541705 | 0.81 | MAPT (0.41) | ALDH1A1TDP1CYP1A2HPGDABCB11 | |
| SCHEMBL6542194 | 0.81 | MAPT (0.41) | ALDH1A1TDP1CYP1A2HPGDABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200050-B1 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2004-09-22 | — | — | EP | disclosed |
| US-6755872-B1 | ALDEHYDE OR KETONE AND NITROAMINE HETEROAROMATICS; NO OXIDING AGENT REQUIRED; COLORFASTNESS; GREY COVERAGE; COLOR DEPTH | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-06-29 | — | — | US | disclosed |
| EP-1200050-A2 | DYEING AGENT FOR KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001010379-A3 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KGAA (DE) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001010379-A2 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | disclosed |