Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682828 | 0.84 | S1PR1 (0.46) | S1PR1S1PR3TRPV1 | |
| SCHEMBL6492242 | 0.81 | GCGR (0.49) | GRM4KDRGCGRTRPV1 | |
| SCHEMBL6799242 | 0.81 | CHRNB2 (0.59) | GRM4KDRKMT2ANPC1RAB9A | |
| SCHEMBL6685612 | 0.80 | S1PR1 (0.46) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL6796384 | 0.79 | SMO (0.55) | GRM4KDRTRPV1 | |
| SCHEMBL6681703 | 0.78 | S1PR1 (0.44) | KDRS1PR1S1PR3 | |
| SCHEMBL6683660 | 0.77 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL6793810 | 0.77 | KDR (0.52) | GRM4KDRKMT2ANPC1RAB9A | |
| SCHEMBL6677363 | 0.77 | NPC1 (0.48) | S1PR1S1PR3KMT2ANPC1RAB9A | |
| SCHEMBL6683684 | 0.74 | HTR2A (0.47) | KDRS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |