Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.65 |
| ▸ | MALT1 | Q9UDY8 | 8/20 | 0.42 |
| ▸ | OXTR | P30559 | 5/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132303 | 0.90 | PTGS2 (0.81) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6686662 | 0.87 | PTGS1 (0.47) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6681239 | 0.86 | PTGS1 (0.64) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6680327 | 0.85 | PTGS1 (0.45) | PTGS1PTGS2OXTRAVPR1AAVPR2 | |
| SCHEMBL6691220 | 0.85 | PTGS1 (0.63) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6682151 | 0.85 | PTGS1 (0.47) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6684505 | 0.84 | PTGS1 (0.64) | PTGS1PTGS2MALT1OXTRAVPR1A | |
| SCHEMBL6132346 | 0.84 | PTGS2 (0.81) | PTGS1PTGS2MALT1OXTR | |
| SCHEMBL6681832 | 0.81 | PTGS1 (0.57) | PTGS1PTGS2MALT1 | |
| SCHEMBL6681738 | 0.80 | PTGS2 (0.58) | PTGS1PTGS2MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |