Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.34 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684307 | 0.89 | PTGS2 (0.47) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6681239 | 0.88 | PTGS1 (0.64) | PTGS1PTGS2MCHR1OXTRAVPR2 | |
| SCHEMBL6682106 | 0.88 | PTGS2 (0.60) | PTGS1PTGS2MALT1 | |
| SCHEMBL6132606 | 0.87 | PTGS2 (0.57) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6687455 | 0.86 | PTGS2 (0.42) | PTGS1PTGS2MALT1 | |
| SCHEMBL6686275 | 0.85 | PTGS2 (0.43) | PTGS1PTGS2MALT1DYRK3CDK2 | |
| SCHEMBL6680327 | 0.84 | PTGS1 (0.45) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6689709 | 0.83 | PTGS1 (0.46) | PTGS1PTGS2OXTRAVPR2AVPR1A | |
| SCHEMBL6132382 | 0.80 | PTGS2 (0.57) | PTGS1PTGS2 | |
| SCHEMBL6689504 | 0.79 | PTGS1 (0.49) | PTGS1PTGS2OXTRAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |