Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 16/20 | 0.75 |
| ▸ | FABP3 | P05413 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685674 | 0.87 | FABP4 (0.74) | FABP4FABP3 | |
| SCHEMBL6686446 | 0.86 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL30398078 | 0.86 | FABP4 (1.00) | FABP4FABP3 | |
| SCHEMBL6691727 | 0.85 | FABP4 (0.74) | FABP4FABP3HDAC1HDAC6 | |
| SCHEMBL30317332 | 0.82 | FABP4 (0.69) | FABP4FABP3 | |
| SCHEMBL28983430 | 0.81 | FABP4 (0.67) | FABP4FABP3 | |
| SCHEMBL30317503 | 0.81 | FABP4 (0.67) | FABP4FABP3 | |
| SCHEMBL6692111 | 0.80 | FABP4 (0.86) | FABP4FABP3 | |
| SCHEMBL30317526 | 0.79 | FABP4 (0.67) | FABP4FABP3 | |
| SCHEMBL28983440 | 0.78 | FABP4 (0.68) | FABP4FABP3PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |