Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806672 | 0.89 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL27570542 | 0.87 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL28482651 | 0.87 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL2808091 | 0.86 | KDM4E (0.57) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL5327265 | 0.83 | KDM4E (0.50) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL5489960 | 0.83 | KDM4E (0.50) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL28679886 | 0.83 | KDM4E (0.64) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL5094605 | 0.83 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL28043812 | 0.82 | KDM4E (0.48) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL625521 | 0.79 | KDM4E (0.48) | KDM4EKMT2AMEN1TDP1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |