Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27871751 | 0.86 | KDM4E (0.55) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL31423245 | 0.85 | KDM4E (0.53) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL27565198 | 0.85 | KDM4E (0.53) | KDM4EKMT2AMEN1TDP1GABRP | |
| Acetic Acid SCHEMBL28329525 | 0.83 | KDM4E (0.52) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL6682995 | 0.82 | KDM4E (0.53) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL27570542 | 0.82 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL26041582 | 0.81 | KDM4E (0.53) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL9276293 | 0.79 | KDM4E (0.52) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL2806672 | 0.79 | KDM4E (0.59) | KDM4EKMT2AMEN1TDP1GABRP | |
| SCHEMBL5327265 | 0.78 | KDM4E (0.50) | KDM4EKMT2AMEN1TDP1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440023-A | Synthetic method of EPZ-6438 | UNIV JIANGSU TECHNOLOGY | 2016-03-30 | — | — | CN | claimed |
| CN-104066718-B | Substituted benzene compounds | EPIZYME股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105037360-B | Pyridione derivatives and its production and use | 四川大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105440023-A | Synthetic method of EPZ-6438 | UNIV JIANGSU TECHNOLOGY | 2016-03-30 | — | — | CN | disclosed |
| CN-105037360-A | Pyridone derivative, preparation method and application thereof | UNIV SICHUAN | 2015-11-11 | — | — | CN | disclosed |
| CN-104066718-A | Substituted benzene compounds | EPIZYME INC | 2014-09-24 | — | — | CN | disclosed |