Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2253252 | 0.86 | PARP10 (0.74) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL2354790 | 0.86 | PARP10 (0.75) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL3021297 | 0.85 | PARP10 (0.74) | PARP10SMN1; SMN2MAOBPARP15PARP14 | |
| SCHEMBL2089763 | 0.84 | PARP10 (0.73) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL3647210 | 0.84 | PARP10 (0.73) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| Hydrochloric Acid SCHEMBL3643418 | 0.84 | PARP10 (0.73) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| Hydrochloric Acid SCHEMBL3648598 | 0.83 | PARP10 (0.71) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB | |
| SCHEMBL1732629 | 0.82 | PARP10 (0.69) | PARP10KDM4EALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL30320388 | 0.82 | PARP10 (0.69) | PARP10KDM4EALDH1A1SMN1; SMN2MAPK14 | |
| SCHEMBL18356194 | 0.82 | PARP10 (0.69) | PARP10KDM4EALDH1A1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| CN-101835752-A | Heterocyclic amides useful for the treatment of cancer and psoriasis | ASTRAZENECA AB | 2010-09-15 | — | — | CN | disclosed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |