Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5676512 | 0.76 | ADORA1 (0.54) | ADORA1MEN1LMNAMAPTKMT2A | |
| SCHEMBL7770354 | 0.65 | ADORA1 (0.67) | ADORA1MEN1LMNAMAPTKMT2A | |
| SCHEMBL9829266 | 0.65 | CA9 (0.60) | MEN1LMNAMAPTKMT2ACA9 | |
| SCHEMBL11626923 | 0.64 | CA9 (0.62) | MEN1MAPTKMT2ACA9CA2 | |
| SCHEMBL7001600 | 0.64 | ADORA1 (0.67) | ADORA1MEN1LMNAMAPTKMT2A | |
| SCHEMBL5675281 | 0.63 | ADORA1 (0.70) | ADORA1MEN1LMNAMAPTKMT2A | |
| SCHEMBL16007300 | 0.63 | ADORA1 (0.80) | ADORA1MEN1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9620531 | 0.63 | GAA (0.64) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL28458172 | 0.63 | MAPT (0.63) | MEN1MAPTKMT2A | |
| SCHEMBL8801153 | 0.62 | MAPK1 (0.65) | MEN1LMNAMAPTKMT2ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727258-B2 | E.G., KETONE DERIVATIVES OF THIENOTHIOPYRANS, BENZOTHIOPHENES, THIENOPYRIDINES, CYCLOPENTATHIOPHENES, THIOPHENYLNAPHTHALENES, THIOPHENYLBENZOFURANS, ETC. | KING PHARMACEUTICAL RESEARCH & DEVELOPMENT, INC. | 2004-04-27 | — | — | US | claimed |