Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 4/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626923 | 0.90 | CA9 (0.62) | MAPK1CA9CA2KDM4EALDH1A1 | |
| SCHEMBL10620940 | 0.88 | KDM4E (0.57) | MAPK1CA9KDM4EALDH1A1MEN1 | |
| SCHEMBL10623071 | 0.84 | CYP2C19 (0.54) | MAPK1CA9KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL11701330 | 0.83 | CYP2C19 (0.53) | MAPK1CA9KDM4EALDH1A1MEN1 | |
| SCHEMBL10620292 | 0.82 | MAPK1 (0.62) | MAPK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10623622 | 0.81 | ABCB1 (0.57) | MAPK1KDM4EALDH1A1KMT2ACYP2C19 | |
| SCHEMBL3051727 | 0.81 | CA9 (0.82) | CA9CA2KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10755161 | 0.80 | CA9 (0.81) | CA9CA2KDM4EMEN1KMT2A | |
| SCHEMBL10625297 | 0.80 | ALDH1A1 (0.56) | MAPK1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10625318 | 0.79 | CYP2C19 (0.70) | MAPK1KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051141-A | ANTIINFLAMMATORY, VASODILATOR, ANTICOAGULANTS | CENTRE D'ETUDES POUR L'INDUSTRIE PHARMACEUTIQUE (FR) | 1977-09-27 | — | — | US | claimed |
| EP-0522956-B1 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI SA (FR) | 1997-02-05 | — | — | EP | disclosed |
| US-5191090-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0522956-A2 | Preparation of 2-(2-thienyl) ethylamine and synthesis of thieno [3,2-C] pyridine derivatives therefrom | SANOFI (FR) | 1993-01-13 | — | — | EP | disclosed |
| US-5068360-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0439404-A2 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI (FR) | 1991-07-31 | — | — | EP | disclosed |
| US-4997945-A | Ticlopidine intermediate | SYNTEX (U.S.A.) INC. (US) | 1991-03-05 | — | — | US | disclosed |
| US-4906756-A | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives | SYNTEX (U.S.A.) INC. (US) | 1990-03-06 | — | — | US | disclosed |
| US-4749692-A | COMBINATION OF SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1988-06-07 | — | — | US | disclosed |
| US-4537894-A | ADMINISTERING SULFINPYRAZONE AND PYRIDINE DERIVATIVE | SANOFI, S.A. (FR) | 1985-08-27 | — | — | US | disclosed |
| US-4464377-A | SYNERGISTIS BETA-ADRENERGIC BLOCKERS AND TICLOPIDINE | SANOFI-SYNTHELABO (FR) | 1984-08-07 | — | — | US | disclosed |
| US-4051141-A | ANTIINFLAMMATORY, VASODILATOR, ANTICOAGULANTS | CENTRE D'ETUDES POUR L'INDUSTRIE PHARMACEUTIQUE (FR) | 1977-09-27 | — | — | US | disclosed |