Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683260 | 0.78 | RAB9A (0.48) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4355899 | 0.76 | RAB9A (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2PLAAT5 | |
| SCHEMBL4358609 | 0.76 | POLB (0.40) | MAPTPOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4351245 | 0.67 | TRPV1 (0.58) | RAB9ANPC1MAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL4342367 | 0.67 | HTT (0.47) | RAB9ANPC1MAPTPOLBALDH1A1 | |
| SCHEMBL6250660 | 0.65 | CNR1 (0.52) | RAB9ANPC1MAPTPOLBALDH1A1 | |
| SCHEMBL4358600 | 0.64 | POLB (0.52) | RAB9ANPC1MAPTPOLBALDH1A1 | |
| SCHEMBL2703124 | 0.64 | HDAC3 (0.60) | RAB9ANPC1MAPTPLAAT5PLAAT4 | |
| SCHEMBL4350095 | 0.64 | MAPT (0.46) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4349030 | 0.63 | RAB9A (0.49) | RAB9ANPC1ALDH1A1PLAAT5PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |