Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689709 | 0.89 | PTGS1 (0.46) | PTGS1PTGS2L3MBTL1GABRA1GABRG2 | |
| SCHEMBL5865649 | 0.87 | PTGS2 (0.60) | PTGS1PTGS2L3MBTL1NPC1RAB9A | |
| SCHEMBL6132473 | 0.86 | PTGS2 (0.67) | PTGS1PTGS2L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL6681657 | 0.84 | PTGS1 (0.52) | PTGS1PTGS2L3MBTL1GABRA1GABRG2 | |
| SCHEMBL6681240 | 0.82 | PTGS2 (0.60) | PTGS1PTGS2L3MBTL1HIF1ANPSR1 | |
| SCHEMBL6132192 | 0.82 | PTGS2 (0.63) | PTGS1PTGS2L3MBTL1HPGDHIF1A | |
| SCHEMBL6132484 | 0.82 | PTGS2 (0.63) | PTGS1PTGS2L3MBTL1HPGDHIF1A | |
| SCHEMBL6684663 | 0.82 | PTGS1 (0.62) | PTGS1PTGS2L3MBTL1GABRA1GABRG2 | |
| SCHEMBL28806023 | 0.81 | PTGS2 (0.60) | PTGS1PTGS2L3MBTL1HIF1ANPSR1 | |
| SCHEMBL27905338 | 0.81 | PTGS2 (0.60) | PTGS1PTGS2L3MBTL1HIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |