Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680340 | 0.88 | EPHX2 (0.36) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL6683830 | 0.81 | HTR2C (0.45) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL7054932 | 0.79 | HTR2C (0.43) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL6682696 | 0.78 | EPHX2 (0.36) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL6680351 | 0.78 | EPHX2 (0.41) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL6684558 | 0.78 | MEN1 (0.37) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL6685217 | 0.77 | HTR2C (0.37) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL6682397 | 0.77 | HTR2C (0.37) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| SCHEMBL6683992 | 0.75 | HTR2C (0.35) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 | |
| Hydrochloric Acid SCHEMBL6683440 | 0.74 | HTR2C (0.37) | HTR2CHTR2ASLC6A4HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305306-B1 | 2-ADAMANTYLETHYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RES LTD (GB) | 2004-11-24 | — | — | EP | claimed |