SCHEMBL668354

SCHEMBL668354

CCCCNC(Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.58
FAAH O00519 2/20 0.54
MME P08473 3/20 0.51
ACE P12821 2/20 0.51
CPA1 P15085 2/20 0.51
ACE2 Q9BYF1 2/20 0.51
LMNA P02545 1/20 0.51
GGT1 P19440 1/20 0.50
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
SIGMAR1 Q99720 1/20 0.47
HDAC3 O15379 2/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668355 1.00 BCHE (0.58) BCHEFAAHMMEACECPA1
SCHEMBL249801 0.95 BCHE (0.54) BCHEFAAHMMEACECPA1
SCHEMBL249802 0.95 BCHE (0.54) BCHEFAAHMMEACECPA1
SCHEMBL3143813 0.95 BCHE (0.54) BCHEFAAHMMEACECPA1
Ethylenediamine SCHEMBL9008938 0.94 BCHE (0.54) BCHEFAAHMMEACECPA1
Ethylenediamine SCHEMBL9008941 0.94 BCHE (0.54) BCHEFAAHMMEACECPA1
SCHEMBL6702717 0.94 FAAH (0.55) BCHEFAAHMMEACECPA1
SCHEMBL6702715 0.94 FAAH (0.55) BCHEFAAHMMEACECPA1
SCHEMBL21585496 0.94 FAAH (0.55) BCHEFAAHMMEACECPA1
SCHEMBL3953856 0.94 FAAH (0.55) BCHEFAAHMMEACECPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219933-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACID THERAPEUTICS ENTRADA THERAPEUTICS, INC. (US) 2023-11-16 WO claimed
EP-3291826-A1 ANTI-BACTERIAL AGENTS AND THEIR USE IN THERAPY Norwegian University of Science and Technology (NTNU) (NO) 2018-03-14 EP claimed
WO-2016177899-A9 ANTI-BACTERIAL AGENTS AND THEIR USE IN THERAPY NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU) (NO) 2016-12-29 WO claimed
WO-2016177899-A1 ANTI-BACTERIAL AGENTS AND THEIR USE IN THERAPY NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU) (NO) 2016-11-10 WO claimed
EP-3065759-A1 IMMUNOSUPPRESSIVE AGENTS AND THEIR USE IN THERAPY Norwegian University of Science and Technology (NTNU) (NO) 2016-09-14 EP claimed
CN-105143245-A Anti-scaling material YISSUM RES DEV CO 2015-12-09 CN claimed
WO-2015067712-A1 IMMUNOSUPPRESSIVE AGENTS AND THEIR USE IN THERAPY NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (NTNU) (NO) 2015-05-14 WO claimed
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications PALATIN TECHNOLOGIES, INC. (US) 2023-02-09 US disclosed
EP-4100040-A1 DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES Palatin Technologies, Inc. (US) 2022-12-14 EP disclosed
EP-4100042-A1 REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES Palatin Technologies, Inc. (US) 2022-12-14 EP disclosed
US-20220204450-A1 Orally Active Melanocortin Receptor-4 Compounds PALATIN TECHNOLOGIES, INC. (US) 2022-06-30 US disclosed
WO-2021158463-A1 DIAMINE-LINKED RECEPTOR-SPECIFIC CYCLIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2021-08-12 WO disclosed
WO-2021158464-A1 REVERSE AMIDE-LINKED MELANOCORTIN RECEPTOR-SPECIFIC CYCLIC PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2021-08-12 WO disclosed
WO-2007098420-A2 PEPTIDES THAT BLOCK THE BINDING OF IGG TO FCRN SYNTONIX PHARMACEUTICALS, INC. (US) 2007-08-30 WO disclosed
EP-1263471-A2 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS ALPHARMA AS (NO) 2002-12-11 EP disclosed
WO-2001066147-A2 ANTIMICROBIAL COMPOUNDS AND FORMULATIONS ALPHARMA AS (NO) 2001-09-13 WO disclosed
EP-0773956-A1 PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Aventis Pharma S.A. (FR) 1997-05-21 EP disclosed
US-5582814-A COMPLEX OF PARAMAGNETIC METAL AND 1-/PARA-BUTYLBENZYL/DIETHYLENETRIAMINEPENTAACETIC ACID METASYN, INC. (US) 1996-12-10 US disclosed
WO-1996004298-A1 PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME RHONE-POULENC RORER S.A. (FR) 1996-02-15 WO disclosed
WO-1995028179-A1 CONTRAST AGENTS FOR DIAGNOSTIC IMAGING METASYN, INC. (US) 1995-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040236-A1 Diamine-Linked Melanocortin Receptor-Specific Cyclic Peptides for Ocular Indications MC1R, MC3R, MC5R BCHE 2523/4885FAAH 1293/4885MME 139/4885
US-20220204450-A1 Orally Active Melanocortin Receptor-4 Compounds MC4R, MC1R, MC3R BCHE 4239/4885FAAH 2873/4885MME 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.