Methacrylic Acid

Methacrylic Acid

SCHEMBL6683573

C=C(C)C(=O)O.NC(=O)OCC=CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
TSHR P16473 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRM3 P20309 1/20 0.31
CYP2C19 P33261 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8770680 0.84
SCHEMBL538269 0.84
Methacrylic Acid SCHEMBL4373868 0.83 TSHR (0.42) TDP1TSHR
Methacrylic Acid SCHEMBL27654285 0.80 TSHR (0.40) TSHR
Methacrylic Acid SCHEMBL8541099 0.80 TSHR (0.40) TSHR
SCHEMBL10606524 0.76 TSHR (0.47) TDP1TSHR
SCHEMBL37916 0.76 TSHR (0.47) TDP1TSHR
Methacrylic Acid SCHEMBL28106238 0.76 ALOX15 (0.58) ALOX15TDP1LMNATSHRCYP2C19
Methacrylic Acid SCHEMBL27788001 0.75 TSHR (0.36) ALOX15TSHR
Ethylene SCHEMBL8679128 0.75 TSHR (0.45) TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675141-B2 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 2004-09-29 EP disclosed
EP-0675141-B1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEM PLASTIC (US) 1998-06-03 EP disclosed
EP-0675141-A1 Copolymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-10-04 EP disclosed
US-5412049-A Polymer compositions containing hydroxyl functional (meth)acrylates and hydroxyalkyl carbamate (meth)acrylates and mixtures thereof UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-05-02 US disclosed