Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30252317 | 1.00 | ADRB2 (0.46) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL7217187 | 0.80 | ADRB2 (0.41) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL19518928 | 0.80 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL17790152 | 0.80 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL6678856 | 0.80 | ADRB2 (0.47) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL3789761 | 0.80 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL8540894 | 0.78 | ADRB2 (0.50) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL1431673 | 0.78 | NISCH (0.58) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL13879241 | 0.78 | ADRB2 (0.50) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL17834115 | 0.78 | ADRB2 (0.46) | ADRB2ADRB1NISCHAOC3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427410-B | Amide or sulfonamide derivatives and application thereof | 苏州恩华生物医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115427410-A | Amide or sulfonamide derivative and application thereof | 苏州恩华生物医药科技有限公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-2021213353-A1 | AMIDE OR SULFONAMIDE DERIVATIVE AND USE THEREOF | 苏州恩华生物医药科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |