Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.64 |
| ▸ | CDK2 | P24941 | 1/20 | 0.64 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 2/20 | 0.56 |
| ▸ | GSK3B | P49841 | 6/20 | 0.56 |
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754813 | 0.84 | CCNE1 (0.68) | CCNE1CDK2NOX4PDE4APDE4B | |
| SCHEMBL13080904 | 0.83 | RET (0.67) | CCNE1CDK2NOX4PDE4APDE4B | |
| SCHEMBL1851097 | 0.83 | RET (0.67) | CCNE1CDK2NOX4PDE4APDE4B | |
| SCHEMBL1851095 | 0.83 | RET (0.67) | CCNE1CDK2NOX4PDE4APDE4B | |
| SCHEMBL1395341 | 0.81 | NOX4 (0.69) | NOX4RETGSK3BPLK4MAPT | |
| SCHEMBL1395339 | 0.81 | NOX4 (0.69) | NOX4RETGSK3BPLK4MAPT | |
| SCHEMBL6405476 | 0.81 | ERBB2 (0.71) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL6405474 | 0.81 | ERBB2 (0.71) | CCNE1CDK2PDE4APDE4BPDE4C | |
| SCHEMBL13080514 | 0.80 | CCNE1 (0.66) | CCNE1CDK2NOX4PDE4APDE4B | |
| SCHEMBL3754352 | 0.79 | NOX4 (0.67) | CCNE1CDK2NOX4RETGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |