SCHEMBL66838

SCHEMBL66838

OB(O)c1cccc(-c2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 1.00
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
ENPP2 Q13822 6/20 0.59
CA4 P22748 1/20 0.59
CA6 P23280 1/20 0.59
CA5A P35218 1/20 0.59
CA7 P43166 1/20 0.59
CA14 Q9ULX7 1/20 0.59
CA5B Q9Y2D0 1/20 0.59
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
PLG P00747 1/20 0.49
F12 P00748 1/20 0.49
F11 P03951 1/20 0.49
KLKB1 P03952 1/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
PCSK9 Q8NBP7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992604 1.00 MGLL (1.00) MGLLCA1CA2ENPP2CA4
SCHEMBL1542869 0.98 MGLL (0.95) MGLLCA1CA2ENPP2CA4
SCHEMBL30423063 0.98 MGLL (0.95) MGLLCA1CA2ENPP2CA4
SCHEMBL29641494 0.98 MGLL (0.95) MGLLCA1CA2ENPP2CA4
SCHEMBL1542734 0.98 MGLL (0.95) MGLLCA1CA2ENPP2CA4
SCHEMBL14653454 0.98 MGLL (0.95) MGLLCA1CA2ENPP2CA4
SCHEMBL12181457 0.96 MGLL (0.91) MGLLCA1CA2ENPP2CA4
SCHEMBL12619984 0.93 MGLL (0.86) MGLLCA1CA2ENPP2CA4
SCHEMBL30712840 0.93 MGLL (0.86) MGLLCA1CA2ENPP2CA4
SCHEMBL31139484 0.93 MGLL (0.86) MGLLCA1CA2ENPP2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2519 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-118459964-B Low-birefringence PC resin composite material and preparation method thereof 拓烯科技(衢州)有限公司 2025-06-03 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119684802-A Nuclear grade high-flame-retardant high-temperature-resistant anti-radiation silicone rubber and preparation method and application thereof 上海电缆研究所有限公司 2025-03-25 CN claimed
CN-119552180-A Hydrolysis-resistant and corrosion-resistant integrated organic borate lubricating oil additive, and preparation method and application thereof 青海大学 2025-03-04 CN claimed
CN-118459964-A Low-birefringence PC resin composite material and preparation method thereof 拓烯科技(衢州)有限公司 2024-08-09 CN claimed
CN-114058045-B Organic room temperature phosphorescent thin film material with hydrothermal stimulus response and excitation dependence, and preparation and application thereof 天津大学 2024-05-07 CN claimed
CN-117568029-A Room-temperature phosphorescent material, and preparation method and application thereof 湖北中烟工业有限责任公司 2024-02-20 CN claimed
CN-113444125-B Phosphoramidite ligand, preparation method thereof and application thereof in asymmetric carbonylation reaction 西北大学 2024-01-26 CN claimed
WO-2024016826-A1 6-POSITION SUBSTITUTED DIHYDROBENZO[E][1,2,3]OXATHIAZINE 2,2-DIOXIDE COMPOUND, PREPARATION THEREFOR, AND USE THEREOF 杭州市第七人民医院 2024-01-25 WO claimed
EP-2739977-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS Massachusetts Institute of Technology (US) 2014-06-11 EP claimed
WO-2013019722-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2013-02-07 WO claimed
US-20130035567-A1 PHOTOLUMINESCENT NANOSTRUCTURE-BASED SENSORS NATIONAL SCIENCE FOUNDATION 2013-02-07 US claimed
US-8361484-B2 Polymer systems for lung volume reduction therapy AERIS THERAPEUTICS, INC. (US) 2013-01-29 US claimed
US-20100040538-A1 Polymer Systems for Lung Volume Reduction Therapy CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2010-02-18 US claimed
EP-2059227-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY Aeris Therapeutics, Inc. (US) 2009-05-20 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
US-7037905-B2 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2006-05-02 US claimed
US-20040053889-A1 Pharmaceutical use of boronic acids and esters thereof NOVO NORDISK A/S (DK) 2004-03-18 US claimed
WO-2003105860-A1 PHARMACEUTICAL USE OF BORONIC ACIDS AND ESTERS THEREOF NOVO NORDISK A/S (DK) 2003-12-24 WO claimed