Egualen

Egualen

SCHEMBL668397

CCc1cc(S(=O)(=O)O)c2cc(C(C)C)cccc1-2

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39
HDAC4 P56524 3/20 0.38
HDAC8 Q9BY41 3/20 0.38
KDM4E B2RXH2 3/20 0.38
HDAC2 Q92769 2/20 0.38
CA2 P00918 2/20 0.38
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MDM4 O15151 1/20 0.38
CA1 P00915 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
TYR P14679 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
CA5A P35218 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Egualen SCHEMBL10805301 0.99 FABP3 (0.38) FABP3FABP4FABP5HDAC4HDAC8
Egualen SCHEMBL442214 0.99 FABP3 (0.38) FABP3FABP4FABP5HDAC4HDAC8
Egualen SCHEMBL14482099 0.97 FABP3 (0.37) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL10804152 0.90 FABP3 (0.36) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL10803865 0.89 FABP3 (0.36) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL10810406 0.88 ELANE (0.36) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL7787569 0.87 FABP3 (0.36) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL10803313 0.87 ELANE (0.36) FABP3FABP4FABP5HDAC4HDAC8
SCHEMBL10810625 0.87 ELANE (0.38)
SCHEMBL10803533 0.86 ELANE (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160250217-A1 CRYSTALLINE FORM OF PEMIROLAST RSPR PHARMA AB (SE) 2016-09-01 US claimed
CN-102596202-B Crystalline forms of pemirolast CARDOZ AB 2015-01-21 CN claimed
US-20120329813-A1 Pemirolast for the Treatment of Systemic Low Grade Inflammation CARDOZ AB (SE) 2012-12-27 US claimed
CN-102724982-A PEMIROLAST FOR THE TREATMENT OF SYSTEMIC LOW GRADE INFLAMMATION CARDOZ AB 2012-10-10 CN claimed
EP-2498779-A1 PEMIROLAST FOR THE TREATMENT OF SYSTEMIC LOW GRADE INFLAMMATION Cardoz AB (SE) 2012-09-19 EP claimed
CN-102596202-A Novel crystalline forms of pemirolast CARDOZ AB 2012-07-18 CN claimed
US-20120157415-A1 New Crystalline Form of Pemirolast CARDOZ AB (SE) 2012-06-21 US claimed
WO-2010146348-A9 CRYSTALLINE FORM OF PEMIROLAST CARDOZ AB (SE) 2012-05-03 WO claimed
EP-2443120-A2 NEW CRYSTALLINE FORM OF PEMIROLAST Cardoz AB (SE) 2012-04-25 EP claimed
WO-2011058331-A1 PEMIROLAST FOR THE TREATMENT OF SYSTEMIC LOW GRADE INFLAMMATION CARDOZ AB (SE) 2011-05-19 WO claimed
WO-2010146348-A2 NEW CRYSTALLINE FORM OF PEMIROLAST CARDOZ AB (SE) 2010-12-23 WO claimed
WO-2010146341-A2 NEW CRYSTALLINE FORM OF PEMIROLAST CARDOZ AB (SE) 2010-12-23 WO claimed
WO-2009007679-A2 COMBINATION FOR USE IN THE TREATMENT OF ATHEROSCLEROSIS COMPRISING A MAST CELL INHIBITOR AND A THROMBOXANE A2 ANTAGONIST CARDOZ AB (SE) 2009-01-15 WO claimed
EP-1336602-A1 Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases Scaramuzzino, Giovanni (IT) 2003-08-20 EP claimed
EP-0147915-B1 NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS Kotobuki Seiyaku Co., Ltd. (JP) 1987-05-06 EP claimed
JP-4295419-A None JP disclosed
WO-2025124483-A1 ORAL DRUG DOSAGE FORM FOR TARGETED DRUG DELIVERY BASED ON TRACKING MARKER AND METHODS OF DESIGN AND USE THEREOF Triastek, Inc. (CN) 2025-06-19 WO disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 WO disclosed
JP-H04295419-A ABSORPTION-ACCELERATING AGENT NIPPON SHINYAKU CO LTD 1992-10-20 JP disclosed
US-4595694-A Peptic ulcer treatment KOTOBUKI SEIYAKU CO. LTD. (JP) 1986-06-17 US disclosed