Egualen

Egualen

SCHEMBL442214

CCc1cc(S(=O)(=O)O)c2cc(C(C)C)cccc1-2.[NaH]

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 1/20 0.38
FABP4 P15090 1/20 0.38
FABP5 Q01469 1/20 0.38
KDM4E B2RXH2 3/20 0.37
HDAC4 P56524 3/20 0.37
HDAC8 Q9BY41 3/20 0.37
HDAC2 Q92769 2/20 0.37
CA2 P00918 2/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MDM4 O15151 1/20 0.37
CA1 P00915 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
TYR P14679 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CA5A P35218 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Egualen SCHEMBL14482099 0.99 FABP3 (0.37) FABP3FABP4FABP5KDM4EHDAC4
Egualen SCHEMBL668397 0.99 FABP3 (0.39) FABP3FABP4FABP5KDM4EHDAC4
Egualen SCHEMBL10805301 0.97 FABP3 (0.38) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL10803865 0.91 FABP3 (0.36) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL10804152 0.89 FABP3 (0.36) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL10803313 0.88 ELANE (0.36) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL10803533 0.87 ELANE (0.37)
SCHEMBL10810406 0.87 ELANE (0.36) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL7787569 0.86 FABP3 (0.36) FABP3FABP4FABP5KDM4EHDAC4
SCHEMBL10810625 0.85 ELANE (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102861337-B One kind contains solid formulation of egualen sodium 北京阜康仁生物制药科技有限公司 2017-08-11 CN claimed
CN-101732290-B Stable solid formulation of egualen sodium KOTOBUKI PHARMACEUTICAL CO LTD 2013-08-28 CN claimed
CN-102861337-A Egualen sodium containing solid preparation BEIJING FUKANGREN BIOPHARMACEUTICAL TECHNOLOGY CO LTD 2013-01-09 CN claimed
CN-101732290-A Stable solid formulation of egualen sodium KOTOBUKI PHARMACEUTICAL CO LTD 2010-06-16 CN claimed
CN-101065121-A Therapeutic or preventive composition for gastric mucosa disease KOTOBUKI PHARMACEUTICAL CO LTD (JP) 2007-10-31 CN claimed
EP-0147915-B1 NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS Kotobuki Seiyaku Co., Ltd. (JP) 1987-05-06 EP claimed
US-4595694-A Peptic ulcer treatment KOTOBUKI SEIYAKU CO. LTD. (JP) 1986-06-17 US claimed
EP-0147915-A1 New azulene derivatives useful as anti-ulcerative and anti-flammatory agents Kotobuki Seiyaku Co., Ltd. (JP) 1985-07-10 EP claimed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles Triastek, Inc. (CN) 2025-06-10 US disclosed
EP-4512394-A2 DOSAGE FORMS AND USE THEREOF Triastek, Inc. (CN) 2025-02-26 EP disclosed
US-20240408023-A1 DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES Triastek, Inc. (CN) 2024-12-12 US disclosed
EP-4171518-B1 RAPIDLY-ORODISPERSIBLE TABLETS HAVING AN INTERIOR CAVITY Aprecia Pharmaceuticals LLC (US) 2024-12-11 EP disclosed
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS Triastek, Inc. (CN) 2024-10-17 US disclosed
WO-1996016656-A1 CONDENSED IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-06-06 WO disclosed
US-5312818-A (Interphenylene)7-oxabicycloheptane substituted (di)amide prostaglandin analog E. R. SQUIBB & SONS, INC. (US) 1994-05-17 US disclosed
EP-0448274-A2 Use of a thromboxane A2 receptor antagonist for the manufacture of a medicament for the treatment of ulcerative gastrointestinal conditions E.R. SQUIBB & SONS, INC. (US) 1991-09-25 EP disclosed
EP-0147915-B1 NEW AZULENE DERIVATIVES USEFUL AS ANTI-ULCERATIVE AND ANTI-FLAMMATORY AGENTS Kotobuki Seiyaku Co., Ltd. (JP) 1987-05-06 EP disclosed
US-4595694-A Peptic ulcer treatment KOTOBUKI SEIYAKU CO. LTD. (JP) 1986-06-17 US disclosed
EP-0147915-A1 New azulene derivatives useful as anti-ulcerative and anti-flammatory agents Kotobuki Seiyaku Co., Ltd. (JP) 1985-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324856-B2 Oral drug dosage form comprising drug in the form of nanoparticles CYP2D6, CYP3A5, CYP3A7 FABP3 3498/4885FABP4 2900/4885FABP5 3466/4885
US-20240342094-A1 COMPARTMENTED PHARMACEUTICAL DOSAGE FORMS CYP2D6, CYP3A5, CYP2F1 FABP3 3746/4885FABP4 2678/4885FABP5 3250/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.