Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL512374 | 0.74 | MEN1 (0.44) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL4447105 | 0.71 | MEN1 (0.41) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL3666780 | 0.70 | MEN1 (0.47) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL963045 | 0.69 | MEN1 (0.42) | MEN1CYP2C9KMT2AALDH1A1 | |
| SCHEMBL23579515 | 0.69 | MEN1 (0.42) | MEN1CYP2C9KMT2APNMT | |
| SCHEMBL23579161 | 0.69 | MEN1 (0.42) | MEN1CYP2C9KMT2APNMT | |
| SCHEMBL11716598 | 0.69 | MEN1 (0.42) | MEN1CYP2C9KMT2APNMT | |
| SCHEMBL6688090 | 0.68 | DPP4 (0.44) | PNMT | |
| Hydrochloric Acid SCHEMBL23579257 | 0.68 | MEN1 (0.41) | MEN1CYP2C9KMT2A | |
| SCHEMBL7308988 | 0.67 | CYP2C9 (0.44) | MEN1CYP2C9KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246791-B1 | AMINOMETHYL-PHENYL-CYCLOHEXANONE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2004-10-27 | — | — | EP | claimed |