SCHEMBL6688090

SCHEMBL6688090

CC1(c2ccccc2)CCCCC1(N)N

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.44
PNMT P11086 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30312220 0.74 OPRM1 (0.50) PNMT
SCHEMBL6390257 0.74 ALDH1A1 (0.43) DPP4
SCHEMBL9421247 0.74 DPP4 (0.47) DPP4PNMT
SCHEMBL11307256 0.73 OPRL1 (0.47) DPP4
SCHEMBL15778080 0.73 MAOA (0.45) PNMT
SCHEMBL11307404 0.72 SLC6A4 (0.44) DPP4
SCHEMBL11307986 0.72 AKR1C1 (0.46)
SCHEMBL28427244 0.71 PNMT (0.46) DPP4PNMT
Hydrochloric Acid SCHEMBL15777055 0.71 MAOA (0.43) PNMT
SCHEMBL8611829 0.71 OPRM1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1246793-B1 SUBSTITUTED AMINOMETHYL-PHENYL-CYCLOHEXANE DERIVATIVES GRUENENTHAL GMBH (DE) 2004-11-10 EP claimed