Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 4/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154575 | 0.83 | GUSB (0.61) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6156436 | 0.82 | GUSB (0.49) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6154359 | 0.81 | GUSB (0.65) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6154135 | 0.81 | GUSB (0.75) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6155142 | 0.80 | GUSB (0.60) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6690137 | 0.79 | GUSB (0.48) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6153840 | 0.79 | GUSB (0.58) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6156141 | 0.77 | GUSB (0.48) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6153546 | 0.77 | GUSB (0.49) | GUSBKMT2AMEN1POLBCTDSP1 | |
| SCHEMBL6153748 | 0.77 | GUSB (0.54) | GUSBKMT2AMEN1POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |